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In practical terms, the difference is small enough that standard dosing protocols do not adjust for it
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This results in a pronounced increase in the intratumoral interstitial fluid pressure (IFP), 16 forming an IFP gradient that favors the flow of interstitial fluid from tumors through the surrounding stroma and into areas of lower IFP, thereby enabling tumor cells and tumor-derived compounds to more readily access LNs
ATP synthase: from sequence to ring size to the P/O ratio
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