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Mental Wellness NAC regulates glutamate, the excitatory neurotransmitter that causes anxiety and obsessive thoughts when levels rise too high
Moderate ulcerative colitis, mostly controlled on mesalamine but still dealing with daily urgency and food reactivity that made eating out feel like Russian roulette
Stroke recovery research: Despite mixed overall results, specific populations (severe stroke, motor recovery focus) show meaningful benefit
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It is synthesised in the cytosol by glutamate-cysteine ligase (EC 6.3.2.2) and glutathione synthetase, with the first, rate-limiting step feedback-inhibited by glutathione itself and intracellular concentrations typically 1 to 8 mM (Griffith, Free Radical Biology and Medicine, 1999)
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