In preclinical models, Dihexa has shown the ability to increase synaptic markers like synaptophysin, improve neuronal counts in the hippocampus, and restore spatial memory and learning capacity in cognitively impaired animals
The FDA also warns that there are no injectable products approved to lighten the skin
However, the use of animal models is expensive, requires a lot of time and expertise, has low throughput potential, poses ethical issues, but most importantly, these models often do not correlate to human systems (Barr-Sinoussi and Montagutelli 2015)
New methods like oral and transdermal glutathione supplementation, along with nutritional interventions, are being explored to boost glutathione level in ASD patients
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