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It works by: Slowing gastric emptying , which prolongs feelings of fullness after eating Reducing appetite through effects on brain regions that regulate hunger Improving glycaemic control by enhancing insulin secretion when blood glucose is elevated Promoting weight loss through reduced caloric intake Wegovy is administered as a once-weekly subcutaneous injection, with doses gradually increased over 1620 weeks to minimise gastrointestinal side effects
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With proper medical supervision and regular follow-up visits, semaglutide GLP-1 therapy can provide sustained appetite regulation
However, because these observations rely solely on immunohistochemistry, they indicate potential involvement rather than providing definitive mechanistic evidence, and molecular validation is required to confirm these pathways
Breastfeeding itself contributes to postpartum weight loss, as lactation requires additional calories daily
