Consequently, there are different possibilities of direct actions of GH as well as endocrine or autocrine/paracrine effects of IGF-I on the cardiovascular system
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Meanwhile, dual and triple agonists targeting receptors beyond GLP-1R are continuously developed in preclinical models
182-182 Gnoni, A., Longo, S., Gnoni, G
The weight loss achieved varies by specific medication and dose: semaglutide 2.4 mg (Wegovy) produces approximately 15% weight loss, tirzepatide (Zepbound) up to 15-22%, and liraglutide 3 mg (Saxenda) about 5-8%