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Regulatory Timelines & What Could Change Access The availability of new and more effective oral GLP-1 medications depends entirely on the outcomes of regulatory reviews
In animal studies, these types of benefits were noted, independent of weight loss
So, what do GLP-1 drugs do
Those can include: Renal complications such as kidney stones Blood glucose dysregulation Irritability The issue of insulin resistance and glucose dysregulation is fraught with contradictions in the research, with some papers asserting that exogenous BCAAs could be a cause for insulin resistance and others claiming that genetic predisposition to diabetes and dysfunctional BCAA metabolism exist in parallel but lack a causal relationship
However, there are on the horizon no cardiorenal outcome studies comparing SGLT-2 inhibitors with GLP-1RA, so it is likely that we must rely on indirect comparisons
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