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The Endocrine Society's framework for off-label peptide prescribing emphasizes that "patient-reported outcomes, captured systematically, are the best available proxy for efficacy in the absence of RCT data." (16) Frequently asked questions How does BPC-157 affect daily life

Semaglutide is typically prescribed for adults with a BMI of 30 or higher (obesity), or a BMI of 27 or higher (overweight) with at least one weight-related condition such as high blood pressure or type 2 diabetes

Hormone Metab Res (2009) 41(8):58593