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A., Wharton, S., & STEP 5 Study Group

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Purified membranes were resuspended in 40 mL low salt buffer and incubated with 100 M PF-06372222, 2 mg mL 1 iodoacetamide, and EDTA-free protease inhibitor cocktail tablet for 1 h at 4 C

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Discussion Using data from the STEP 1 and STEP 2 phase 3 trials, we found broad effects from subcutaneous semaglutide treatment in people with overweight or obesity (with and without T2D) on the circulating proteome compared with placebo