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Together, they may help protect cells from oxidative stress

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Prog Neuropsychopharmacol Biol Psychiatry 20:11591170 Holmay MJ, Terpstra M, Coles LD, Mishra U, Ahlskog M, Oz G, Cloyd JC, Tuite PJ (2013) N-Acetylcysteine boosts brain and blood glutathione in Gaucher and Parkinson diseases

For instance, investigations into the efficacy of compounds like Rehmannioside A or the role of HMGB1 in astrocyte-mediated iron dysregulation have been conducted in mice subjected to transient MCAO, albeit with varying occlusion times (e.g., 90 min