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Without dose-finding studies, this remains guesswork

Key Signs and Symptoms to Watch For Typical symptoms of medication-related constipation If you are experiencing constipation, you might notice one or more of the following symptoms: Having fewer bowel movements than what is normal for you (e.g., less than three per week)

Take care if you have liver disease or low body weight, and check other medicines don't also contain paracetamol

Zhang J, Pavlova NN, Thompson CB

B12 is delivered through an IV infusion by inserting a small catheter into a vein, allowing a saline-based solution containing vitamin B12 to flow directly into the bloodstream