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Recent guidelines for non-alcoholic fatty liver disease (NAFLD)/ fatty liver disease (FLD): are they already outdated and in need of supplementation

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For weight management, NICE has approved liraglutide 3 mg (Saxenda) and semaglutide 2.4 mg (Wegovy) under specific criteria, including BMI thresholds and provision through specialist weight management services

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Exendin-4 Ex-4 has been shown to enhance pancreatic beta-cell marker expression (pancreatic and duodenal homeobox 1 ( PDX-1 ), NK2 homeobox 2 ( NKX2.2) , ISL LIM homeobox 1 (I SL-1 ) and v-Maf musculoaponeurotic fibrosarcoma oncogene homolog A ( MAFA)) [35,36,37]

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