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Various factors, including hyperglycemia, lipid accumulation, oxidative stress, hypoxia, RAAS, ER stress, inflammation, EMT and programmed cell death, have been shown to induce renal tubular injury and contribute to the progression of DKD
D.HigginsD
Selenium is a cofactor for an enzyme called glutathione peroxidase
Probiotics : Certain strains may enhance gut health and potentially stimulate GLP-1 secretion
2 DPP4 predominantly exists as dimers on the cell surface and is widely distributed throughout the body, being present in epithelial cells, certain endothelial cells, leukocyte subsets, and fibroblasts
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