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Berberine is another supplement some users combine with semaglutide for additional metabolic support, though it should be introduced carefully due to its own effects on the gut microbiome

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Methods Older adults ( 65 years) across Canada participated in an online survey, which included the VR-12, a PROM measuring physical and mental health, and the Screening for Poverty and Related social determinants to improve Knowledge of and links to resources (SPARK) tool, a measure of various SDOH (i.e., demographics, social needs, and disabilities)

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