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Michalak, E
In human studies, Nrf2 suppression has been linked to cataract formation in lenses collected from diabetic and older patients, with the upregulation of Keap1 (an Nrf2 suppressor) found in these individuals
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Enzymes involved in lipid metabolism may also be the appropriate target to prevent the formation of brain metastases, because oncogenic lipid signaling can promote the metastasis of breast tumor cells to the brain by supporting cell survival, migration, and invasion (154)
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