Alfthan G, Aro A, Arvilommi H, Huttunen JK
[PMID: 3782149] PubMed record related to this compound for laboratory literature review
Engineering of two surface-exposed cysteines into the GFP barrel on the two adjacent -strands 7 and 10 in positions allowing reversible disulfide formation exploits a structure-dependent shift in the protonation status of the chromophore for ratiometric measurements (Dooley et al., 2004
Data from the STEP [52] and SUSTAIN [53, 54] trials consistently demonstrate that the substantial weight loss achieved with semaglutide at doses of 0.5 mg, 1.0 mg, and 2.4 mg is largely independent of these symptoms, with less than 1% of the total weight loss benefit attributable to GI AEs
For mass spectrometric analysis, sample processing was further proceeded with reduction and alkylation, followed by acetone precipitation and tryptic digestion