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BPC-157, TB-500 and GHK-Cu are used in in-vitro systems, ex-vivo tissue explants and animal models to study endpoints such as endothelial-cell activity in angiogenesis assays, fibroblast-associated matrix gene expression, cell migration and wound closure

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For topical formulations, concentrations of 0.1 to 0.3 percent are used, with efficacy detectable from as low as 0.01 percent