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In sepsis-associated acute lung injury, transcription of Myosin Light Chain Kinase mediated by the serum response factor (SRF) can prevent ferroptosis in polymorphonuclear neutrophils [53]
However, its levels naturally decline with age, and obtaining sufficient amounts through diet alone can be challenging
doi:10.1038/s41598-024-65310-y Neelakantan H, Hommel JD, Watowich SJ, et al
SARM1, another NADase, rapidly consumes NAD + following axon damage, resulting in neuronal degeneration 7,53,54
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