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This does not mean joint discomfort never occurs, but rather that it may be uncommon or secondary to other mechanisms

The FDA classifies compounded semaglutide and tirzepatide as Category C (animal effects observed, no human data), making preconception discontinuation the conservative, evidence-supported standard

They set up a policy where compounders could work around FDA approval guidelines in cases of shortages." But right now, there is no shortage of GLP-1 medications, and because companies like Eli Lilly and Novo Nordisk have patents, patients are likely years away from FDA-approved generics

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