Several factors can increase the likelihood of experiencing GLP-1 hair loss: Rate of weight loss: Faster weight loss places greater stress on the body, increasing the chance of telogen effluvium
A 2019 meta-analysis in European Journal of Endocrinology found that each 10% reduction in body weight was associated with a 2-3 nmol/L increase in total testosterone, placing the weight loss achieved with tirzepatide well within the range needed for clinically meaningful hormonal improvement (Corona et al., 2019, European Journal of Endocrinology )
Patients should be monitored for signs of inadequate nutritional intake, particularly elderly patients or those with low baseline body weight, as determined relevant by the prescribing clinician
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