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Initially, senescence was confirmed through SA--gal staining following treatment with 4 M of CDDP (Figure
GHK-Cu demonstrated remarkable effects in 5xFAD Alzheimer's mice: reduced amyloid plaques in multiple brain regions, decreased neuroinflammation (measured by MCP-1 staining intensity), and improved cognitive performance (Y-maze testing) approaching wild-type control levels
However, measuring cytotoxicity alone is not sufficient
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