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The retrospective, observational nature of our study and the use of prescription data must be acknowledged as limitations because they meant that some relevant factors could not be captured and accounted for in our analyses

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For weight management in people without diabetes, NICE recommends considering specific GLP-1 agonists (semaglutide 2.4mg or liraglutide 3mg) only in specialist weight management services, for individuals with a BMI 35 kg/m (or 32.5 kg/m for people from South Asian, Chinese, other Asian, Black African, or African-Caribbean backgrounds) who have weight-related comorbidities