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If a patient reports persistent injection site discomfort that is not resolving within 24 to 48 hours, copper sensitivity is the first thing we evaluate

Most semaglutide efficacy data comes from monotherapy trials (SUSTAIN, SELECT) demonstrating 10-15% weight loss over 68 weeks

Combines appetite suppression with increased metabolic rate from glucagon agonism

Who Profits Who Profits: Novo Nordisk (NVO) FY2024 Revenue: $61.0B | GLP-1 Revenue (Ozempic + Wegovy): $26.0B | Net Profit: $14.6B | CEO (Lars Fruergaard Jorgensen): $11.8M This issue's mechanism: Novo Nordisk's profit is fundamentally tied to GLP-1 pricing