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Gastroenterology 156 , 19411950 (2019)

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Ozempic (semaglutide) affects reward pathways involved in appetite and alcohol craving, but alcohol reward also involves opioid signaling that GLP-1 medications may not directly target

"It was the best decision and the best thing I did for my body in a very long time," Williams said.

The difference likely relates to the specific conformational changes each agonist induces in the receptor, which determines which G-protein pathways are preferentially activated