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This multicountry trial was conducted in accordance with the International Conference on Harmonization Good Clinical Practice guidelines and the Declaration of Helsinki and was approved by local institutional review boards

Food and Drug Administration and European Medicines Agency, and UK SmPC hosting via the electronic Medicines Compendium (emc), plus pharmacovigilance-oriented publications using FAERS (and, where available, broader databases)

10.1074/jbc.M113.545301 J

They may prescribe a lower dose of insulin or sulfonylurea to mitigate the risk of low blood sugar