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According to the Mayo Clinic, one of the most common medical uses of B-12 shots is for pernicious anemia

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Established low ranges are often too low, and researchers have found that normal-low B12 levels have been associated with neurological symptoms such as difficulty balancing, memory lapses, depression, mania, fatigue, and even psychosis

They are often combined for a synergistic effect

Effectiveness and safety of low molecular weight heparin in the management of acute pancreatitis: a systematic review and meta-analysis