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Liu DX, Zhao CS, Wei XN, Ma YP, Wu JK
p53-pS15 is a major focal point in p53 activation to mediate p53-dependent transcription or growth arrest, Ser 15 phosphorylation triggers a sequence of additional sites phosphorylation in p53 (including Ser9, -20, -46 and Thr18) that contribute further to p53 activation 28
Beta cell function and the nutritional state: dietary factors that influence insulin secretion
The committee gave two reasons
The same study showed a 25% improvement in metabolic health markers with the maintenance dose, indicating benefits that extend beyond mere weight loss
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