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Siddiqui A et al
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The rationale for adding it to tirzepatide is that calorie restriction and GI side effects from GLP-1 medications can reduce B12 absorption, potentially leading to deficiency over time
As a result, it can be regarded a possible alternative for reducing COVID-19-induced fatigue, and its use is encouraged in future clinical trials to assess its efficacy and safety (Vaziri-Harami and Delkash, 2022)
Certain gut bacteria metabolize this unabsorbed carnitine into a compound called Trimethylamine (TMA)
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