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Blocking TLR2 activity reduces mortality, attenuates cardiac dysfunction, and inhibits myocardial fibrosis in doxorubicin-induced cardiomyopathy

Future research should focus on large-scale, well-controlled randomized trials with standardized dosing protocols, clearly defined deficiency thresholds, and long-term follow-up to strengthen the evidence base and guide clinical practice

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Genetically, ASD can be linked to identifiable genetic syndromes, such as Fragile X, Tuberous Sclerosis, Neurofibromatosis I, ADNP syndrome, and copy number variations (Lubbers et al., 2024