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Dosage and Titration Schedule Mounjaro is started at a low initial dose to help minimise side effects, particularly gastrointestinal symptoms such as nausea

Treatment outcomes may be affected by under- or over-dosing as a result of improper mixing

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Reduced MTHFR activity reduced methionine regeneration reduced SAM production reduced methylation capacity across all SAM-dependent methyltransferase reactions consequences that propagate through epigenetics, neurotransmitter metabolism, creatine synthesis, phosphatidylcholine production, and the broader biochemistry that SAM sustains