As mentioned, due to the fact that GPLC has been found to greatly increase Nitric Oxide levels within the human body, more oxygen and nutrients can be transported to the awaiting muscle cells, and as a result, the muscles can function more efficiently before they begin to tire and fatigue
Also, a small non-randomized study 15 in two older adults treated with ALC (2 g/day for 12 weeks), reported a decrease in HDRS scores from 15 to 0 and from 20 to 3 by week 12 and compared outcomes with six non-depressed controls
In addition to Munger, key support for this study was provided by Wilmot investigators Brad Mills, PhD, and Brian Altman, PhD.
Its dysregulation not only reflects impaired energy homeostasis but may also directly influence stem cell fate, proliferation, and differentiation, further highlighting its crucial role in ALS pathophysiology
This gives them more control over their treatment