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Formularies can change
Standard community protocols run retatrutide alone for the first 4 weeks at 1 mg weekly to confirm GI tolerance, then add MOTS-c at Week 5
Most clinical practice guidance recommends sequential or monitored approaches rather than automatic combination
This transition is expected to expand patient access and increase adoption of GLP-1-based therapies
It delivers doses in 2-unit increments and can deliver up to 160 units in a single injection
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