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However, the effects of GLP-1 agents and other glucose-lowering drugs on cancer risk are not well established
The published Phase 3 mean weight reduction for retatrutide (28.3%) is nearly double the figure reported for semaglutide in STEP-1 (14.9%) over comparable trial durations [1][2][9]
Ma T, Du X, Pick JE, Sui G, Brownlee M, Klann E
the compound 1 used in the patent is not easy to obtain (the synthesis steps are relatively more, the cost is higher) and has low purity (in the process of preparing the compound 1 from the compound 6 in the previous step, the N-succinimide is easily removed while the tert-butyl group is removed)
There was no restriction based on the original language of the article
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