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doi: 10.1093/jee/83.6.2443 201 OmamtE

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[33] first documented a reduced incretin effect in patients, with type 2 diabetes

Should this pharmacological profile be confirmed in late-stage clinical studies, optimized FGF21 analogs have the potential to not only resolve liver pathology, but also to reduce risk of cardiovascular morbidity and mortality, and incidence of organ damage associated with inadequate glycemic control

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