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Short-acting versions (taken daily) may cause sharper peaks in nausea but might be cleared from the system faster

GLP-1s also target the hunger center in your brain to reduce your appetite and slow gastric emptying (the rate food leaves your stomach) which helps you feel full and reduce your food intake

Better choice of diet and activities has great potential to reduce the rate of telomere shortening or at least prevent excessive telomere attrition, leading to delayed onset of age-associated diseases and increased lifespan

The following individual and combined search terms were used: GLP-1, Semaglutide and Liraglutide, molecular mechanism, lipid metabolism, insulin metabolism, glucose homeostasis, energy expenditure obesity treatment, type 2 diabetes mellitus, side effects, clinical trials, treatment option, fatty liver disease, hypertension, neurodegenerative diseases, cardiovascular diseases, therapeutic options. Only articles published in the last 10 years are included, although older pivotal studies were added