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NNMT inhibition restores the cellular machinery needed for efficient fat burning
"The beneficial effect of BPC 157, a 15 amino acid peptide BPC fragment, on gastric and duodenal lesions induced by restraint stress, cysteamine, and 96% ethanol in rats." Journal of Physiology Paris
The Billon 2025 paper introducing SLU-PP-915 (PMID 41421047) describes the parent compound SLU-PP-332 as lacking oral bioavailability the orally active sibling SLU-PP-915 was developed because of that limitation
Low levels can also cause anemia, which can make it harder for the body to transport oxygen to the fetus and other organs
NNMT connects nicotinamide metabolism with the cellular methyl-donor system
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