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Clinical relevance: Liraglutide has been largely supplanted by weekly GLP-1 alternatives (semaglutide, tirzepatide) due to inferior efficacy and daily injection requirement

According to one small study, GI symptoms topped the list of side effects for people using semaglutide for weight loss, with fatigue coming in at a close second

Patients need more than a prescription

Unlike simpler single-receptor agonist peptides, retatrutide is a complex 39-amino-acid synthetic peptide

When combined with healthy habits, they can help support your joints over time, making the future feel a little more mobile and a lot more hopeful.