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JCI Insight (2020) 4
The Evaluate Renal Function with Semaglutide Once Weekly (FLOW) trial, published earlier this year, is the first to specifically investigate kidney outcomes with GLP-1 receptor agonists
Myalgia typically starts in childhood while myoglobinuria starts later in adolescence or early adulthood [1]
Mean weight reductions were greater with all cagrilintide doses (roughly 6.0% to 10.8%) than with placebo (3.0%), and the top 4.5 mg dose modestly out-performed the active comparator, once-daily liraglutide 3.0 mg (10.8% vs 9.0%)
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