In subjects with T2DM, weekly administration of tirzepatide at doses of 5 mg, 10 mg, or 15 mg was associated with greater weight loss compared to placebo ( 6.3 kg, 8.4 kg, and 9.4 kg, respectively), and 1.7 kg, 4.8 kg, and 7.2 kg greater weight loss compared to selective GLP-1 receptor agonists, demonstrating a dose-dependent effect sustained for up to 2 years [48]
It is a melanin inhibitor as it inactivates the enzyme tyrosinase
First 4 weeks : Small changes in appetite and eating habits often begin
Red flag: Avoid any provider who claims there are "zero risks." All medical interventions carry some level of risk
An oxygen saturation in this range should not generally cause cyanosis (usually the oxygen saturation must be substantially lower before cyanosis occurs)