Endogenous GLP-1 has several functions, including triggering insulin release from the pancreas, as well as decreasing appetite and digestion, and this drug class mimics the GLP-1 hormone
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Splitting it up to three doses per day with meals is a way to combat these effects
BioMed Research International 2022:112 Hu J, Liu R, Yu X, Li Z, Liu X, Hao Y, Zhu N, Kang J, Li Y (2021) Protective effects of small-molecule oligopeptides isolated from tilapia fish scale on ethanol-induced gastroduodenal injury in rats