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But the NHS has slowed its roll-out of these drugs among those who are eligible because they are worried that the cost of the drugs and the large number possible users might mean GLP-1s take up around half the entire national budget for all drugs

Cumulative intake was 33.9% lower versus vehicle control

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It says research combining fasting with GLP-1 medications remains limited, and that most clinical data covers weight loss and glycemic control under standard treatment rather than the safety of extended fasting periods