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Physiol 302 , R274282, (2012)

These drugs are altering that particular part of the drug absorption phase, says Archana Sadhu, an endocrinologist at Houston Methodist Hospital, adding that this effect can be particularly prominent during dosage increases

Think of it this way: GLP-1 therapy opens the door to significant fat reduction, but without attention to muscle preservation, some of what walks out that door is tissue the body cannot easily afford to lose