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A trial published in The New England Journal of Medicine (2023) demonstrated mean weight reductions of up to approximately 24% of body weight over 48 weeks in adults with obesity a potentially significant finding if confirmed in Phase 3 trials

Effective wound filling and infection prevention are crucial, especially in cases of irregularly shaped wounds 60,61

The study population included a broad range of subjects with varying severities of RI: mild, moderate, severe, and a group with ESRD undergoing regular hemodialysis

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In animal studies, intermittent fasting prevented obesity