Food and Drug Administration (FDA) has approved Wegovy as a prescription medicine for some people for weight loss
GLP-1 receptor signaling regulates insulin secretion, glucose homeostasis, appetite and gastrointestinal function
Recently, a phase II multicentre, double-blind, randomized controlled trial including 338 adults with obesity were administered retatrutide (1, 2 mg starting dose increased to 4, 2 mg starting dose increased to 8, 2 mg starting dose increased to 12 mg) compared to placebo over 48 weeks [64]
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Gut and Liver, 14(2), 153-167