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doi: 10.7759/cureus.442 274

A low SAM/SAH ratio may result from insufficient SAM, elevated SAH or both

En animales e insectos, la glutamato cistena ligasa (GCL) es una enzima heterodimrica compuesta por un catalizador (GCLC) y subunidad moduladora (GCLM)

The MTR enzyme is ubiquitously expressed, whereas another hcy remethylation system, mainly expressed in the liver and in the kidneys, involves the betaine-homocysteine methyltransferase (BHMT) enzyme (Obeid, 2013)