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Exposure to NPs through inhalation or systemic administration can cause NPs accumulation in organs such as the lungs, liver, or kidneys with inflammation or neurotoxicity ( Table 1 Nanoparticle used for the treatment of neurodegenerative diseases

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Ohara H, Matsumoto H, Ito K, Iwai K, Sato K (2007) Comparison of quantity and structures of hydroxyproline-containing peptides in human blood after oral ingestion of gelatin hydrolysates from different sources

A marked induction of GST isoenzymes could contribute to a strong and possibly early symptomless type of resistance, while a less increase or a decrease of GST activity may confer only a weak virus resistance that eventually results in susceptibility (Gullner et al., 1995b)

The Journals of Gerontology: Series A, 69(Suppl 1), S4-S9