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doi:10.1038/ng1297-491

On the maximum dose of a GLP-1 drug taken consistently, and for an adult who is 50-75 pounds overweight, expected outcomes of weight lost over 3-12 months are: 3 months: 1015 lb 6 months: 2030 lb 9 months: 2540 lb 12 months: 3050+ lb Based upon the 2018 Bariatric study data by Jansen, et al, patients lost on average 32.1 kg (70 lbs) in 12 months

According to the case report, published in JAAD Case Reports, researchers described the lesions as "initially erythematous and pruritic reactions [that] subsequently progressed into asymptomatic chronic hyperpigmented patches with an erythematous border." Physical examination revealed "multiple dusky hyperpigmented round patches with erythematous borders on her buttock and abdomen." A 4-mm punch biopsy from the right buttock demonstrated "lichenoid interface dermatitis

Tirzepatide is a groundbreaking medication that combines the effects of GLP-1 and GIP receptor agonism to reduce appetite, improve blood sugar control, and promote significant weight loss

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