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In contrast to other GPxs, GPx4 is the only one that reduces the hydroperoxides of lipoproteins and complex lipids, such as cholesterol, cholesterol esters, and phospholipids [108], to protect mitochondrial ATP generation from oxidative damage [109]

For vitamin B12 deficiency caused by autoimmune gastritis, or after a total gastrectomy or complete terminal ileal resection, NICE recommends lifelong intramuscular replacement

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B12 injections offer an alternative way to achieve optimal levels

This is why wall-directed slow injection without agitation is non-negotiable in controlled research settings