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Inflammatory responses increase oxidative stress and oxygen free radicals, which impair GAG synthesis

Probiotic supplementation significantly decreased serum oxidative stress markers while increasing antioxidant capacity in Hashimotos thyroiditis patients (da Silva et al., 2023)

Ashour AE, Sayed-Ahmed MM, Abd-Allah AR, Korashy HM, Maayah ZH, Alkhalidi H, et al

There are over 50 hormones that affect hundreds of processes throughout your body metabolism, mood, blood pressure, body temperature, sexual function, and more.14 When it comes to sex hormones, males and females actually have the same ones (estrogen, testosterone, and progesterone), but their production, concentrations, and interactions with the rest of the body are different.15 So, even though were focusing on female hormones in this guide, well be discussing testosterone in addition to estrogen and progesterone all of them are produced by the ovaries in people assigned female at birth (AFAB).14 Pivoting to their effects on health, its worth clarifying that you dont need to have a diagnosable hormone imbalance to experience bothersome symptoms due to or exacerbated by female hormone fluctuations

However, current TCM research in PCOS primarily focuses on the general modulation of the gut microbiota, with limited attention given to ferroptosis-specific mechanisms