For skin and connective tissue support, some researchers layer in GHK-Cu for wound healing
They are particularly beneficial for vegetarians and vegans (since B12 is found primarily in animal products), older adults with reduced absorption capacity, individuals with digestive conditions such as Crohn's disease or celiac disease, and anyone who has had gastric bypass surgery
After finishing a general surgery residency at Cornell, he completed a one-year fellowship at Mount Sinai specializing in gastric bypass, sleeve gastrectomy, revisional bariatric surgery, anti-reflux operations, and hernias
At the Endocrine Societys 2025 meeting, researchers tracked 110 men with obesity or type 2 diabetes treated with semaglutide, dulaglutide, or tirzepatide, none of them on hormone therapy
What it does not reproduce is the mechanical loading of actual exercise, so tendon, bone, and connective-tissue adaptations are not part of the promise