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Author contributions JX: Data curation, Formal analysis, Methodology, Software, Validation, Visualization, Writing original draft

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Preclinical data suggests that triple agonism may shift the ratio of fat-to-lean mass loss in a more favorable direction

Research context: Ingredient-level studies examine isolated compounds under controlled conditions

Notably, GLP-1Rs have also been found in the atrial cavities and in the sinoatrial node, still their precise physiological function remains unclear (32)